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Modular super-enhancer controls retinal development

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell… Source link

NIH researchers develop first stem cell model of albinism to study related eye conditions

Researchers at the National Eye Institute (NEI) have developed the first patient-derived stem cell model for studying eye conditions related to oculocutaneous albinism (OCA). The model’s… Source link

Could Eyedrops Replace Reading Glasses?

More than one-third of Americans have presbyopia, a gradual loss of near vision with age. Most people reach for eyeglasses or specialty contact lenses, but these are easily lost or can seem burdensome. Now, a… Source link

UC Irvine researchers reveal molecular mechanisms of eye disease using cryo-electron tomography

 Krzysztof Palczewski and his research team at the University of California Irvine revealed key structural determinants of rod photoreceptors–one of two major types of light-sensing cells in the… Source link

The First Alternative to a Monthly Injection for Wet AMD

There’s a new way to deliver sight-saving treatment for wet age-related macular degeneration (wet AMD) and it may make living with the chronic eye condition a lot easier. People with wet AMD need eye injections of a… Source link

Pathway to better eye health runs through the gut

Chronic noninfectious uveitis is a form of eye inflammation that, if left untreated, leads to vision loss and even blindness. Current treatments use broad anti-inflammatory medications such as… Source link

Happy Holidays from Belmont Eye Center

Link found between lupus, macular degeneration

Jayakrishna Ambati, M.D. Jayakrishna Ambati, University of Virginia, and colleagues reported that genetic material called short interspersed nuclear element RNAs (SINE RNAs) send immune factors… Source link

Cataract surgery does not cause disease progression in people with AMD

People with age-related macular degeneration (AMD) can undergo cataract surgery without fear of worsening their disease, according to the latest analysis of data from the Age-related Eye Disease… Source link

NIH researchers identify potential AMD drugs with stem-cell based research tool

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists…. Source link

Reimagining immunity in the eye

In a new study, the researchers show that immune cells respond to the lens, not just following an acute injury in the eye, but also to long-lasting inflammation. (Feed generated with FetchRSS) Source link

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NIH study traces molecular link from gene to late-onset retinal degeneration

Scientists have discovered that gene therapy and the diabetes drug metformin may be potential treatments for late-onset retinal degeneration (L-ORD), a rare, blinding eye disease. Researchers from… Source link

Study: Cataract surgery linked with lessened dementia risk

Cataracts affect most older adults at risk for dementia, and now researchers are finding strong evidence that cataract surgery is associated with a lower risk of developing dementia. Cecilia Lee,… Source link

A New Microscope for Imaging Neural Circuitry

Advancing our understanding of the human brain requires new insights into how neural circuitry works in mammals, including laboratory mice. These investigations require monitoring brain activity with… Source link

NIH scientists discover new B cell that tempers autoimmunity

Researchers at the National Eye Institute (NEI) have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation. Infusions… Source link

Which side is which? How the brain perceives borders

In the classic “Rubin’s vase” optical illusion, you can see either an elaborate, curvy vase or two faces, noses nearly touching. At any given moment, which scene you perceive depends on whether… Source link

Neurobiologists Reveal How Value Decisions are Coded into Our Brains

In 2019 University of California San Diego researchers discovered the area of the brain where “value decisions” are made. An area within the cerebrum known as the retrosplenial cortex… Source link

CU Researchers Provide First Evidence Linking Extracellular Vesicles with Drusen Formation and Age-Related Macular Degeneration

CellSight researchers at the University of Colorado School of Medicine are offering the first evidence connecting drusen formation, or yellowish deposits that accumulate under the retina, with… Source link

Retinoid Therapy May Improve Vision in People with Rare Genetic Disorder, According to Study in Mice

Using data generated from patients and mice with genetic mutation for the disorder Usher syndrome, researchers from the University of Maryland School of Medicine (UMSOM), the National Institutes of… Source link

Small amounts of carbon monoxide may help protect vision in diabetes

An ingested liquid that ultimately delivers a small dose of carbon monoxide to the eye appears to target key factors that damage or destroy vision in both type 1 and 2 diabetes, scientists say. The… Source link

Air Pollution Can Cause Eye Problems, Study Shows

New research suggests living in a city with poor air quality increases your chance of developing age-related macular degeneration (AMD)—a leading cause of blindness. The study, published in the British Journal of… Source link

Paintball Guns, Toy Guns, and Other Projective Toys Cause Serious Eye Injury and Blindness

Paintball Guns and Ballistic Goggles: A Tactical Combination Air guns are a notorious threat to the eyes. But new findings suggest these guns are harming more eyes than ever before. Eye injuries from paintball,… Source link

How COVID Increased the Need for Eye Removal

When the COVID-19 pandemic began in March 2020, Carol Shields, M.D., director of the Ocular Oncology Service at Wills Eye Hospital in Philadelphia, saw a dramatic drop in the number of patients in her office. Even… Source link

NEI unveils “Vision for the Future”

The National Eye Institute has released a new strategic plan. 2021 Vision for the Future charts the next five years of NEI’s mission: to eliminate vision loss and improve quality of life through vision… Source link

Researchers Discover New Type of Nerve Cell in the Retina

Scientists at the John A. Moran Eye Center at the University of Utah have discovered a new type of nerve cell, or neuron, in the retina. In the central nervous system a complex circuitry of neurons… Source link

Cartography of the visual cortex

One major organizational property the visual cortex employs is called retinotopic mapping, where neurons within are arranged in an orderly way that preserves the spatial information arriving from the… Source link

Prozac Pegged as Potential Treatment for a Leading Cause of Blindness

An antidepressant best known as Prozac could offer the first treatment for the leading cause of blindness among people over 50, new research from the University of Virginia School of Medicine… Source link

Genomic Study Revealing Among Diverse Populations with Inherited Retinal Disease

An international team of researchers, led by scientists at University of California San Diego and Shiley Eye Institute at UC San Diego Health, has broadened and deepened understanding of how… Source link

A new treatment for glaucoma?

A Northwestern Medicine study in mice has identified new treatment targets for glaucoma, including preventing a severe pediatric form of glaucoma, as well as uncovering a possible new class of… Source link

Learning how transplanted neurons fit in

New projects funded through the National Eye Institute’s Audacious Goals Initiative (AGI) aim to enhance the survival and integration of regenerated neurons in the visual system … Source link

AMD: Reading ability crucial indicator of functional loss

In geographic atrophy, a late form of age-related macular degeneration (AMD), reading ability is closely related to the altered retinal structure. This has been demonstrated by researchers from the… Source link

Why Is Dry Eye So Difficult to Treat?

Many people with dry eye feel misunderstood and unsatisfied with their treatment, a new survey shows. Here’s why treating the disease is so difficult and what ophthalmologists say could help. (Feed… Source link

Eye Exams May Help Identify Seniors at Risk of Dementia

Eye exams in aging adults may catch more than just vision problems. A new study bolsters evidence that certain types of vision problems may point to an elevated risk of dementia. The Academy recommends all healthy… Source link

Early Signs of Heart Disease Appear in the Eyes

Eye doctors may be able to detect signs of heart disease during a comprehensive eye exam, experts say. A new study finds that people with heart disease tend to have retinas marked by evidence of eye stroke.  Eye… Source link

Toxic DNA Buildup May Drive Macular Degeneration

Damaging DNA builds up in the eyes of patients with geographic atrophy, an untreatable, poorly understood form of age-related macular degeneration that causes blindness, new research from the… Source link

EyeCare America: Healthy Eyes Happy Lives Infographic

One in six Americans age 65 and older has a vision impairment that cannot be corrected with glasses or contact lenses. The risk of eye disease increases with age, yet many… Source link

Most People Don’t Use Marijuana for Glaucoma, Study Shows

If perception is reality, then it’s a good idea to know what people think about marijuana’s role in glaucoma therapy. A team of ophthalmologists and epidemiologists in Colorado, one of the 34 states that have… Source link

Living Retina Achieves Sensitivity and Efficiency Engineers Can Only Dream About

If you wanted to design the most perfect, low-energy, light-detecting device for a future camera or a prosthetic retina, you’d reach for something called ‘efficient coding theory,’ to set out the array of sensors. Or you could just look at a mammalian retina. In a pair of papers on retinal structure, Duke University neurobiologists have […]

NIH-funded study shows screening device accurately detects amblyopia (lazy eye)

A handheld screening device that detects subtle misalignment of the eyes accurately identifies children with amblyopia (lazy eye), according to a study published in the Journal of American Association for Pediatric Ophthalmology and Strabismus. “The findings suggest that pediatricians and other primary care providers could use the device to catch  amblyopia at an early age […]

Being Diagnosed With Inherited Retinal Dystrophy

Read the story of a woman diagnosed with retinitis pigmentosa (RP), a type of inherited retinal dystrophy. Retinitis pigmentosa is a group of related eye disorders that cause progressive vision loss. These disorders affect the retina, which is the layer of light-sensitive tissue at the back of the eye . In people with retinitis pigmentosa, vision […]

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Research Study: Progression of Myopia in School-Aged Children After COVID-19 Home Confinement

A recent study has cited that there has been a significant decline in the vision of children. This is linked to the COVID-19 home confinement and additional screen time. The most common condition that has developed is Mytopia, also known as nearsightedness. The study indicated that younger children’s refractive status may be more sensitive to […]

Seeing Yellow Spots?

The eye is a complex and delicate structure. When light enters your pupil it gets focused through a lens before hitting your retina. There are unique cells in your retina that convert light into electrical signals that are sent to the brain via the optic nerve. Even slight damage to these complex systems can lead […]

Research Study: Vision Loss Can Effect Brain Function

A recent research study from the JAMA Network titled “Association of Vision Impairment With Cognitive Decline Across Multiple Domains in Older Adults” cites that vision loss can impact the health of the brain. These findings suggest that the association between vision and cognition differs by the measure of vision and that impaired contrast sensitivity is […]

The “COVID-Vision” Crisis

Since the COVID-19 pandemic began, many people switched to working from home and virtual learning. This increased their screen time and hours spent on the computer each day. According to a report by Eyesafe, the average screen time per person rose 60% to more than 13 hours a day, in March 2020. Optometrists say they have […]

Myopia management: Looking after the “other” pandemic

Short sightedness – technically called myopia – affects around three in 10 adults in the UK. It means that distant objects can appear blurry whilst close work generally remains unaffected. On the face of it, this doesn’t sound worrying. However, myopia can create long-term eye health problems, and a recent study estimated that myopia will affect the […]

Low vision patients not routinely tested for dry eye disease despite high risk

Researchers conducted a retrospective chart review of randomly selected patients (aged 26 to 97 years) qualifying under the Quebec health insurance system as low vision, with a BCVA of 20/60 or less in at least one eye, visual field diameter of 60 degrees or those with hemianopsia. The final analysis included 201 adult patients, (mean […]

FACETITE Introduction

FaceTite is a new procedure that is comparable to a surgical facelift, without the large scars. FaceTite provides dramatic improvement in skin laxity on the face and neck, which was previously only attainable through a surgical procedure such as a facelift. FaceTite utilizes minimally invasive radiofrequency energy to melt fat and contour skin. LEARN MORE  

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